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DeCS
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Descriptor English:
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Mixed Connective Tissue Disease
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Descriptor Spanish:
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enfermedad mixta del tejido conjuntivo
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Descriptor Portuguese:
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Doença Mista do Tecido Conjuntivo
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Synonyms English:
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Connective Tissue Disease, Mixed
MCTD
Sharp Syndrome
Syndrome, Sharp
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Tree Number:
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C17.300.540
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Definition English:
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A syndrome with overlapping clinical features of systemic lupus erythematosus, scleroderma, polymyositis, and Raynaud's phenomenon. The disease is differentially characterized by high serum titers of antibodies to ribonuclease-sensitive extractable (saline soluble) nuclear antigen and a "speckled" epidermal nuclear staining pattern on direct immunofluorescence. |
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Indexing Annotation English:
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a specific disease entity; do not confuse with CONNECTIVE TISSUE DISEASES
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History Note English:
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79
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Allowable Qualifiers English:
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Record Number:
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9137
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Unique Identifier:
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D008947
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Occurrence in VHL:
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Similar:
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DeCS
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